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It disrupted mitochondrial integrity and impaired antioxidant defenses via the Nrf2/Gpx4 pathway
12,399 These tools have revolutionized our ability to dissect the biological features of malignant tumor cells, uncover intratumoral heterogeneity and its dynamic evolution, elucidate tumor-immune cell interactions, and uncover mechanisms of drug resistance and relapse, paving the way for personalized treatment strategies to improve patient outcomes (Fig
It is about removing what might be irritating the immune system and developing an environment wherein the stomach lining has a chance to repair
The fitting results show that the mechanism of drug release of GA@Lip and GA@Tf-Lip is First-order release at pH 7.4 and pH 6.8, while it is more fit to erosion at pH 5.5, which indicates that the developed liposomes have a pH-sensitive drug release effect
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