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Handy DE, Lubos E, Yang Y, Galbraith JD, Kelly N, Zhang Y-Y, et al
[36] Eglumetad has also been demonstrated to act on the metabotropic glutamate receptor 3 (GRM3) of human adrenocortical cells, downregulating aldosterone synthase, CYP11B1, and the production of adrenal steroids (i.e
In pancreatic ductal adenocarcinoma, the KRAS mutation induces reverse electron transport via mitochondrial complex I, generating O 2 that activates the MAPK/ERK pro-proliferative signaling axis [395]
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