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In particular, Ras mutations induce dysregulated cell division within thyroid follicular cells, leading to hyperplastic thyroid lesions including nodules (Peterson 2014)
Lezmy J, Arancibia-Crcamo IL, Quintela-Lpez T, Sherman DL, Brophy PJ, Attwell D
83 amino acids Modifications: Arg substitution (GluArg at IGF-1 position 3) for reduced IGFBP-3 affinity
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