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Specific Adverse Effects Reported in Clinical Trials While the overall safety profile was excellent, clinical trials documented all adverse events regardless of severity or causality

gonorrhoeae , and that in several meningococcal lineages the island contains an additional gene, kbuT encoding a transporter from the 4-Toluene Sulfonate Uptake Permease (TSUP) family involved in transport of -ketobutyrate, an -keto acid particularly abundant in polymorphonuclear neutrophils (PMNs) (Mhling et al., 2003), which can be metabolized through the MCC, raising the hypothesis of a role of MCC during meningococcal host cell infection (Tal et al., 2025)

Clin Cosmet Investig Dermatol 2014;7:267