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The practical implication is that classic drug-interaction reasoning built around liver enzymes usually does not transfer, and that renal impairment matters more than hepatic impairment for many of these compounds
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Circulation 140 , 225239 (2019)
Native GLP-1(7-37)-OH, glucagon, BMS21, compound 2, 125 I-GLP-1 and 125 I-glucagon tracer were synthesized by Novo Nordisk A/S
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