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The scientists behind the study detected insulin-stimulated somatostatin (insulin-inhibiting somatostatin) release only when there were low blood glucose levels and glucagon-stimulated somatostatin (glucagon-inhibiting somatostatin) when there were high blood glucose levels

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Diabetes Obes Metab 18(2):178185 Tonneijck L, Smits MM, Muskiet MHA, Hoekstra T, Kramer MHH, Danser AHJ et al (2016) Acute renal effects of the GLP-1 receptor agonist exenatide in overweight type 2 diabetes patients: a randomised, double-blind, placebo-controlled trial

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