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Sam Sukkar, MD on March 3rd, 2026 Grade 1 gyno (grade 1 gynecomastia) is the mildest form of gynecomastia, small, firm glandular breast tissue under the nipple that can make the male breast look slightly puffy without sagging or excess skin

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Changes in hormones like testosterone and estrogen may also lead to hair loss. For example, what if you take tirzepatide but are also going through perimenopause or menopause