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There are three ways that higher blood glucose concentrations are bad[ref]: Damage due to osmosis: High glucose causes dehydration and excessive urination
Not everyone experiences these effects, and when they do occur, theyre generally short-lived
Prevalence is highest in South America and the Middle East (~44%), followed by Asia (27%), Europe (25%), North America (24%), and Africa (14%)
By engaging the glucagon receptor in addition to the two incretin receptors, retatrutide is hypothesized to add a direct energy-expenditure component to the appetite-suppressing and glucose-regulating effects already established for GLP-1 and GIP agonism
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