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Identification of the peptide-antibody fusion MEDI4166 Following expression, V19A and L26I variants showed the highest percentage of monomeric product post-protein A purification and the lowest aggregation after a 4 week 5 C incubation at the target concentration of 50 mg/mL (Supplementary Fig

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Then researchers move to humans so they are confident that it could work and when they are willing to invest in much more expensive research