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The compounded medication risk profile is far enough from standard pharmaceutical malpractice that some carriers exclude it entirely

Lastly, a systematic review and meta-analysis published in Thyroid in 2016 found that selenium significantly reduced thyroid autoantibodies in people with chronic autoimmune thyroiditis

doi:10.1179/1476830514Y.0000000158 Geiselman JF

A randomized, double-blind, placebo-controlled trial in 60 Thai medical students found that glutathione (500 mg/day for 4 weeks) reduced melanin index scores at multiple body sites compared to placebo (Arjinpathana & Asawanonda, J Dermatolog Treat, 2012) [61]