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Journal of Endocrinology , 2001 Demonstrated AOD9604's lipolytic properties and its selective activation of fat metabolism pathways without affecting IGF-1 levels
On the basis of this pharmacokinetic difference, in the ongoing phase 3 clinical trial programme for IcoSema, an initial dose of IcoSema corresponding to 0.114 mg semaglutide has been selected, hence lower than the 0.25 mg recommended as starting dose for semaglutide alone [25,26,27]
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