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This is thought to be a key player in the sexual side effects often experienced by those taking selective serotonin reuptake inhibitors (SSRIs), such as reduced libido and delayed orgasm

A hallmark of ferroptotic initiation and execution is the upregulated peroxidation of phospholipid-bound polyunsaturated fatty acids (PUFAs) within cellular membranes, a process facilitated by labile iron pools (LIPs) and amplified through autocatalytic radical reactions (13,14)

#siRNA #SCAD #CNSdelivery #SOD1ALS Published today in @Nature Medicine

Sleep deprivation also interferes with hunger-related hormonesinsulin, ghrelin and leptinleading to weight gain and insulin resistance, contributing to pre-diabetes and type 2 diabetes