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It can take two to four weeks before the body becomes accustomed to intermittent fasting
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Moreover, new imaging techniques including transient elastography and magnetic resonance imaging-proton density fat fraction (MRI-PDFF) have enhanced the diagnostic capacity but they are not yet widely available for use (65, 66)
The first Phase 3 readout (TRIUMPH-4, December 2025) reported 28.7% mean weight loss at 68 weeks
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