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JAMA Neurol 76(4):420429 Brown JC, Dryburgh JR (1971) A gastric inhibitory polypeptide II: the complete amino acid sequence

Preclinical in vivo models have demonstrated anti-fibrotic effects of incretin receptor agonism in the heart

Because yerba mate contains a decent amount of caffeine, drinking too much of it can also cause some of the side effects associated with excess caffeine intake, such as jitteriness, insomnia, increased heart rate, and elevated blood pressure