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While this is a key research area, we propose that further investigations should verify whether GLP-1RAs may also affect cognitive and behavioral symptoms seen in psychosis, as suggested by their potential to influence neurobiological (for example, immune function) and neuropsychological (for example, reward) mechanisms that are known to be disrupted in psychotic illness

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Sutherland EW, Cori CF, Haynes R, Olsen N et al (1949) Purification of the hyperglycemic-glycogenolytic factor from insulin and from gastric mucosa