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This gradual ramp-up helps minimize gastrointestinal discomfort during the adjustment period
Methods Patients and study design The study protocol was conducted in accordance with the guidelines contained within the Declaration of Helsinki and was approved by the ethics committees of Yokohama City University and Kyoto Prefectural University of Medicine
Do not attempt to self-assess whether a preparation is safe to use following a suspected storage failure
In this case, thats the note C
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