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Upon binding to the receptor, GLP-1 and its analogs also initiate a variety of additional anti-diabetic effects, including, but not limited to, reduction in gastric emptying, increase in satiety and inhibition of food motivated behavior, replenishment of insulin stores, as well as cytoprotective and anti-inflammatory actions on -cells (29)
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Before initiating Zepbound therapy, healthcare providers should conduct a comprehensive personal and family medical history focusing on thyroid disorders and endocrine cancers, with particular attention to MTC and MEN 2
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