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Discontinuation rates are higher among lower-income groups, those with multiple health conditions, and patients over 65
In contrast, systems such as microfluidic-assembled nanocapsules or electrosprayed powders remain below TRL 5 due to cost, complexity, or scalability constraints (194, 195)
Abstract Background: Oxidative stress can result from redox reactions involving hemoglobin (Hb) and nitric oxide (NO), forming toxic peroxynitrite when NO reacts with superoxide during Hb autoxidation
Futhermore, 2025 results from the ATTAIN-MAINTAIN trial demonstrated orforgliprons ability to compete in the maintenance segment
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