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It is a hormone which is involved in the regulation of appetite and controlling blood sugar level
Metformin hydrochloride is freely soluble in water and is practically insoluble in acetone, ether, and chloroform
Most published adverse event summaries rank pruritus (itching) as rare to uncommon, appearing in fewer than 5% of treated patients in major trials
Howard and colleagues at Merck identified the growth hormone secretagogue receptor, GHS-R, expressed in the pituitary and hypothalamus, and showed that the GHRPs and the non-peptide secretagogue MK-677 acted through it
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