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Its not recommended for long-term use (typically limited to 3-4 month cycles), may cause irritation and contact dermatitis, and poses a risk of ochronosis (blue-black discoloration) with prolonged use, particularly in deeper skin tones
Semaglutide is one of several GLP-1 agonists approved for weight loss others are liraglutide (Saxenda) and tirzepatide (Zepbound)
Accessed 11/3/2020, Kelm Z, Klapchar K, Kieliszak CR, Selinsky C
How Tirzepatide Dosing Works Step-by-Step Tirzepatide treatment follows a structured titration protocol designed to minimize nausea and other GI side effects while building to an effective dose
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