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Set X (921 genes) was altered by GLP-1R agonism in both the control and the ethanol diet, but not by ethanol alone

They still support lab studies on its role in cell metabolism

Patients with T2D not adequately controlled on therapy with metformin and insulin glargine as baseline therapy received either tirzepatide at the doses used in the SURPASS trials or placebo during the 40-week study setting