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Although both contain the same active compound, tirzepatide, they serve different medical purposes
Trulicitys rates from the AWARD trials show: nausea (24-29%), diarrhea (18-19%), and vomiting (8-18%)
J Mol Neurosci 76 , 121 (2026)
It follows a set 16-week dose escalation: Weeks 14: 0.25 mg Weeks 58: 0.5 mg Weeks 912: 1 mg Weeks 1316: 1.7 mg From Week 17 onward: Maintenance dose of 2.4 mg This gradual increase is designed to reduce side effects while optimizing the medications weight loss benefits
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