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GLP-1 agonists, designed initially to manage type 2 diabetes, bind and activate receptors located throughout the body, eliciting a biological response similar to naturally occurring GLP-1, a gut-derived hormone usually released after eating fats and carbohydrates

With their cross-biological-system effects, GLP-1s may prove helpful in reducing the impact of some of these factors

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Poor sleep impairs weight loss despite caloric restriction, reduces cognitive function regardless of nootropic support, and elevates stress hormones that work against protocol goals