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Consequently, the tirzepatide group was reduced to three animals by the end of the study

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Elevated hepcidin levels suppress the expression of FPN1, TfR1, and DMT1, thereby limiting iron entry into the brain

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In conclusion, preclinical and emerging clinical evidence are changing the paradigm, viewing incretin receptor agonists solely as metabolic-based therapeutics for treating obesity and diabetes to recognising them as multifaceted agents with significant disease-modifying potential for inflammatory fibrotic disorders across different organ systems

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The modulation of esophageal defenses after the absorption of SCFAs into the bloodstream needs to be further studied and explored

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