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We would also like to thank Tobias Bader and Stewart Bigelow for their technical contributions to this work
Figure 2 Within the SOC level, gastrointestinal system disorders in overall GLP-1 RAs were overreported compared with the background frequency (ROR 1.46, PRR 1.33, IC 0.41, EBGM 1.33), which were further attributed to liraglutide (ROR 2.39, PRR 1.84, IC 0.88, EBGM 1.33), dulaglutide (ROR 1.39, PRR 1.28, IC 0.36, EBGM 1.25), and semaglutide (ROR 3.00, PRR 2.10, IC 1.07, EBGM 2.10), while exenatide (ROR 0.57, PRR 0.63, IC 0.68, EBGM 0.63) and lixisenatide (ROR 0.51, PRR 0.57, IC 0.81, EBGM 0.57) did not show the association with gastrointestinal AEs ( Table 2 )
Keep a food and activity diary for a week or two to identify any patterns
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