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This means that if you inject 5 mg of tirzepatide on Monday: By Saturday (day 5), approximately 2.5 mg equivalent remains in circulation By the following Monday (day 7), approximately 1.9 mg equivalent remains When you inject the next 5 mg dose on Monday, it adds to the 1.9 mg still circulating By week 4 of consistent weekly dosing, you reach steady state, where the amount you inject each week equals the amount eliminated
Start with your pharmacy some will replace a pen if it was shipped during freezing weather or if you picked it up recently
Do not apply to sensitive skin types or apply very sparingly (highly diluted) to avoid excess irritation
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