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Dermatology trials noted spontaneous erections and increased sexual desire, leading to development of bremelanotide
A phase IIb RCT in overweight patients with T2DM showed the efficacy of cotadutide in reducing weight and serum transaminases in comparison with placebo (NCT03235050)
Effectiveness and Side Effects: Semaglutide appears to result in greater weight loss compared to liraglutide, but it is also associated with more frequent side effects
What the Research Is Telling Us Two studies from 2024 have raised big red flags: A study published in JAMA Ophthalmology found that semaglutide users were over four times more likely to develop NAION than those on other diabetes drugs
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