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To assess the importance of lipidation modification to Cagri, pharmacological comparison of Cagri and its non-lipidated backbone (CagriBB) was undertaken using a cAMP response element (CRE)-reporter assay

One familial risk factor is the allele of apolipoprotein E (APOE * 4) associated with Alzheimer's disease (AD) (Saunders et al., 1993)

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