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At this stage, it is more accurate to describe these psychological and QoL improvements as concomitant effects of metabolic and symptomatic relief rather than independent psychopharmacological actions
[1] [2] Clinical trials demonstrate substantial weight reduction, with participants losing an average of 15-21% of body weight over 72 weeks in the SURMOUNT-1 trial
Adding the second compound too early often leads to intense nausea and a forced step-down on one or both compounds
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