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For patients who experience significant GI side effects at standard titration rates, a slower escalation using a lower starting concentration can make treatment more tolerable and improve long-term adherence
But it explains why some individuals respond dramatically at low doses while others need maximum doses to achieve similar effects
doi: 10.3389/fnmol.2024.1441575 10 BirbenESahinerUMSackesenCErzurumSKalayciO
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