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Nephron 144 , 595606 (2020)
Subsequent work has suggested that sustained GIP receptor agonism may resensitise the GIP signalling axis over time, an effect that mono-agonism on GLP-1 alone cannot produce
Adverse events and tolerability The overall proportion of participants experiencing AEs while on treatment was slightly higher for oral semaglutide 7 mg and 14 mg than for oral semaglutide 3 mg and sitagliptin 100 mg, with most AEs being mild/moderate in severity (Table 3)
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