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Three distinct metabolic pathways
It regulates: Satiety signaling Insulin secretion Gastric emptying Postprandial glucose response Energy partitioning This is why the idea that the microbiome controls appetite is better understood as microbiome-influenced appetite signaling, where microbial metabolites may help shape satiety, gastric emptying, and metabolic response
GLP-1 receptor agonism slows gastric emptying, which can increase intra-gastric pressure and promote acid reflux in susceptible individuals
His approach emphasizes evidence-based care, patient safety, and realistic, sustainable results
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