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When the medication stops, the biological pressures that caused weight gain in the first place reassert themselves
Conversely, the randomized, placebo-controlled, phase 3 study by Elkind-Hirsch et al
That slowing can be helpful for weight loss, but it may also affect the absorption of oral medications, including thyroid medication, in some patients
In clinical trials of FDA-approved GLP-1 medications used under medical supervision, some patients achieved average losses consistent with 4 to 8 pounds per month over time, with a total weight loss of roughly 15% to 21% of body weight over the full treatment course
