It mimics growth-hormone-releasing hormone at the pituitary for a brief window (~30 minutes), nudging out a pulse of GH without driving a sustained, tonic rise in IGF-1
Fifth and sixth weeks, etc
* Correspondence: Nemanja Dimic, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Brand Name Details: Medication: Tirzepatide Manufacturer: Eli Lilly FDA Approval: May 2022 Approved For: Type 2 diabetes management Dosing: Once-weekly injection Available Doses: 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg List Price: $1,069 per month How Mounjaro Works: Mounjaro activates two hormone receptors: GIP (Glucose-Dependent Insulinotropic Polypeptide) Effects: Enhances insulin secretion when blood sugar is elevated Improves insulin sensitivity May influence fat metabolism Contributes to appetite suppression GLP-1 (Glucagon-Like Peptide-1) Effects: Increases insulin release after meals Decreases glucagon (prevents excess glucose production) Slows stomach emptying Reduces appetite through brain signaling Increases feelings of fullness This dual action produces: Superior blood sugar control Exceptional weight loss (average 15-22% of body weight) Reduced cardiovascular risk factors Improved metabolic health markers What Is Tirzepatide