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Animals were anesthetized intramuscularly with a ketaminexylazine mixture composed of 30 mg/kg ketamine and 12 mg/kg xylazine, respectively, with a total injection volume of 1.2 mL/kg
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In addition, a change in environmental osmotic stress can cause tissue damage due to the production of free radicals (ROS) (Reference Li, Chen and Zeng9)
The mechanisms, dosing, and effects are the same
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