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120 In addition, hepatic glucose lead to a deficiency in the transcription factor carbohydrate responsive element binding protein (ChREBP) resulting in reduced mRNA levels of glycolytic and lipogenic enzymes, as well as SREBP-1c levels

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The microbial metabolite imidazole propionate dysregulates bone homeostasis by inhibiting AMP-activated protein kinase (AMPK) signaling Suk-Gyun Park, Jung-Woo Kim, Ju Han Song, Seung-Hee Kwon, Sin-Hye Oh, Xianyu Piao, Zhao Wang, Je-Hwang Ryu, Nacksung Kim, Ok-Su Kim, Jeong-Tae Koh Communications Biology .2024;[Epub] CrossRef 6,146 View 122 Download Crossref Original Article Background Osteoporosis prevalence continues to escalate with the growth of the older adult population