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This disruption severely affects cochlear energy metabolism and enhances susceptibility to further ototoxic damage
2000 Sep-Dec;22(5-6):384-92
It should be used in combination with diet and exercise and is approved for adults with obesity or overweight with at least one weight-related condition
At the cellular level, the lack of insulin leads to the activation of alternative metabolic pathways, in which the liver contributes to the increase in blood sugar by increasing gluconeogenesis and glycogenolysis, while adipose tissue undergoes intense lipolysis and releases large amounts of free fatty acids into the bloodstream
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