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This review synthesizes emerging insights into lactates multifaceted roles and discusses promising therapeutic strategies targeting lactate metabolism, transport, and downstream signaling pathways, with an emphasis on candidates advancing toward clinical translation
Here, we used phage-assisted evolution to reprogram botulinum neurotoxin serotype X proteases to cleave and activate procaspase-1 and gasdermin D, key effectors of inflammatory cell death
Progressive improvement in comfort and function
Emerging role of substance and energy metabolism associated with neuroendocrine regulation in tumor cells
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