These include Alzheimers Disease where neuroprotective effects are under investigation followed by stroke under similar notion (125) Futhermore, in non-alcoholic fatty liver disease (NAFLD) they show evidence of improved liver histology and hepatic steatosis (126) in PCOS they may help in regulation of weight, reproductive and metabolic parameters simultaneously (127) GLP1-Ras are also under study with their ability to modulate the hemodynamic and inflammatory pathways to treat CKD (128) and Heart failure (129)
A clinical strategy designed for durability GLP-1 medications like Wegovy and Zepbound are powerful but only when used strategically
Tirzepatides mechanism of action is to: lower food intake stimulate the release of insulin from the pancreas slow down the digestion process reduce the production of glucagon by the liver Together these mechanisms work to reduce appetite and cravings, improving weight loss results when following a diet plan
Through its multifaceted mechanisms of action, including improved glycemic control, weight loss, anti-inflammatory effects, blood pressure regulation, lipid profile improvements, and enhancement of endothelial function, semaglutide provides a comprehensive approach to cardiovascular risk reduction
