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As highlighted in the review, approaches under investigation include hypoxia-activated prodrugs, HIF inhibitors, anti-angiogenic therapies, and metabolic enzyme modulators targeting glycolysis, glutaminolysis, and lipid metabolism
This molecule was discovered by Eccogene and licensed globally to AstraZeneca
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For instance, unimolecular doses of the dual-receptor agonist tirzepatide has effects that closely resemble dulaglutide, a pure GLP-1RA
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