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Both Ruhoy and Kaufman appear to have glommed onto these drugs via the 700-plus doctors MASTERMINDS network of health providers in communication with each other about ME/CFS, FM, MCAS, POTS, long COVID, etc

High homocysteine concentrations may promote the development of atherosclerosis (atherogenesis) and thrombogenesis via mechanisms involving oxidative stress and endothelial dysfunction, inflammation, abnormal blood coagulation, and disordered lipid metabolism (reviewed in 35)

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Titration is the process of starting a medication at a very low dose and gradually increasing it over a period of weeks or months