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Ceases release of glucagon (a hormone secreted by the alpha cells of the pancreatic islets of langerhans during hypoglycaemia)
Eli Lilly is studying the pill in a longer study in people who are overweight or have obesity to see if the weight loss continues
Its primarily used to treat type 2 diabetes a chronic metabolic condition that occurs when the body cant use insulin properly its weight loss benefits are really what nailed down its popularity
Small-molecule orals, such as Lillys orforglipron can be produced through conventional pharmaceutical chemistry and distributed as tablets, without the cold-chain requirements of injectable peptidesopening access to a broader manufacturing ecosystem and potentially different scaling economics
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