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180,181 The arginase isoenzymes arginase1 (ARG1) and arginase2 (ARG2) are abnormally upregulated in various cancers
PMID: 31674057
Yet, keep in mind that most of this research has been conducted with L-carnitine, not ALCAR specifically
Important unresolved questions include long-term toxicology, interaction effects, endocrine and metabolic safety, formulation consistency, validated potency methods, independent replication, and whether adequately powered controlled studies would support broader conclusions
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