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In this pathology, IGF-I levels diverge between studies, from increased to decreased IGF-I concentrations[330332], probably due to differences in samples origin (serum/cerebrospinal fluid vs spinal cord/musculoskeletal) and could be explained as a physiological defensive mechanism promoted in response to the neural degeneration and/or muscle atrophy
doi: 10.1080/00480169.1998.36089
Koeth RA y otros
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