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However, its reactivity has a cost: O 2 strips electrons from biological macromolecules causing the formation of reactive oxygen species (ROS), which induce intracellular damage [24]
But cagrilintide won decisively on tolerability: GI adverse events 54.0% vs 73.8%, and discontinuation for adverse events 2.6% vs 3.6% (cagrilintide was actually below the 3.5% placebo rate)
Mosley, R
The blue curve shows the 95 th percentile and the red curve shows the 5 th percentile
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