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There is a lot of medical literature about this
Allergies If you are allergic to cobalt, you should not take vitamin B12, as vitamin B12 contains a cobalt molecule
Confirmatory diagnostic studies should be performed prior to initiating therapy, if possible, and the patient should be followed with appropriate studies to demonstrate hematologic improvement (Hgb, hematocrit, RBC, reticulocyte count)
This is followed by maintenance injections of 1mg every 2-3 months (or every 2 months with neurological involvement)
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