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The Impact of GLP-1 on the Balance between Bone Formation and Bone Resorption Normal bone metabolism in humans involves both bone formation and bone resorption in a balanced state of equilibrium
In atherosclerotic disease, GLP-1RAs have been shown to attenuate and stabilize development of atherosclerotic plaques through anti-inflammatory mechanisms (inhibition of IL-6 and TNF-, and NF-B), inhibit activation and recruitment of macrophages and prevent vascular remodeling
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