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A meta-analysis of 77 RCTs involving 50,820 patients with T2DM found that compared with placebo, lifestyle modification, or active anti-diabetic drugs, SGLT2is were associated with a significantly higher risk of genital infections (RR, 3.30
Oxidative stress, as reflected by glutathione status, appeared to be an earlier signal than inflammation in the trajectory of age-related cognitive decline
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While scientists have identified several genes associated with Alzheimers risk, understanding how these genes interact with one another and how those interactions differ across brain cell types remains a major challenge
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