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In endothelial progenitor cells (EPC) derived from human peripheral blood mononuclear cells, high glucose conditions downregulate GLP-1-R and sirtuin 1 ( SIRT1 ) expression, leading to impaired cell functions and increased apoptosis via elevated acetylated p53 levels
Machado SA, Pasquarelli-Do-Nascimento G, Da Silva DS, Farias GR, De Oliveira SI, Baptista LB, et al
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