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It contains a cyanide molecule, which is replaced by a methyl or adenosyl group in the body, allowing it to convert into an active form of B12
In-vitro assays show the molecule is membrane-permeable, which supports the possibility of oral absorption, but the animal efficacy studies used injection, and no study has directly compared oral versus subcutaneous bioavailability
If a significant amount of the vitamin B12 in your blood is inactive, a blood test may show that you have normal Vitamin B12 levels, even though your body cannot use much of it.Sometimes it is helpful to just look at the size of your red blood cells or the microcytic volume to see whether they are larger than normal
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